Table 4 NASH scoring of H&E stained liver sections and fibrosis scores in Sirius Red stained liver sections
| Â | Score | MCS (% of cases) | MCD (% of cases) | C1 (% of cases) | C2 (% of cases) | C3 (% of cases) | C4 (% of cases) |
|---|---|---|---|---|---|---|---|
Steatosis | 0 | 100% | 0% | 0% | 0% | 0% | 0% |
| Â | 1 | 0% | 13% | 0% | 0% | 31% | 12% |
| Â | 2 | 0% | 17% | 0% | 0% | 50% | 19% |
| Â | 3 | 0% | 70% | 100% | 100% | 19% | 69% |
Significant | Â | MCD, C1, C2, C3, C4 | MCS, C3 | MCS, C3 | MCS, C3 | MCS, MCD, C1, C2 | MCS |
Portal inflammation | 0 | 88% | 83% | 69% | 21% | 94% | 94% |
| Â | 1 | 12% | 17% | 31% | 79% | 6% | 6% |
Significant | Â | C2 | C2 | C2 | MCS, MCD, C1, C3, C4 | C2 | C2 |
Lobular inflammation | 0 | 27% | 8% | 0% | 0% | 19% | 0% |
| Â | 1 | 67% | 4% | 13% | 13% | 31% | 31% |
| Â | 2 | 2% | 57% | 64% | 64% | 50% | 56% |
| Â | 3 | 4% | 31% | 23% | 23% | 0% | 13% |
Significant | Â | MCD, C2 | MCS | N/S | MCS | N/S | N/S |
Fibrosis | 0 | 12.5% | 0% | 0% | 0% | 0% | 0% |
| Â | 1A | 0% | 18.8% | 0% | 0% | 0% | 0% |
| Â | 1B | 87.5% | 62.5% | 12.5% | 14.3% | 62.5% | 37.5% |
| Â | 1C | 0% | 0% | 0% | 0% | 0% | 0% |
| Â | 2 | 0% | 6.3% | 62.5% | 0% | 37.5% | 50% |
| Â | 3 | 0% | 12.5% | 25% | 85.7% | 0% | 12.5% |
| Â | 4 | 0% | 0% | 0% | 0% | 0% | 0% |
Significant | Â | MCD, C1, C2, C3, C4 | MCS, C1, C2, C3, C4 | MCS, MCD, C2, C3, C4 | MCS, MCD, C1, C3, C4 | MCS, MCD, C1, C2, C4 | MCS, MCD, C1, C2, C3 |